Does sperm contain spermidine?

Mar 04, 2025

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Does Sperm Contain Spermidine?

 

Semen does indeed contain spermidine.

Spermidine is a naturally occurring polyamine and an important intracellular biomolecule. It is present not only in organs such as the human kidneys but also in semen, where it plays a crucial role in sperm maturation and function. Research indicates that reduced spermidine levels are closely associated with male infertility, diminished sperm quality, and miscarriage.

 

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Semen consists of sperm and seminal plasma, which contains abundant bioactive substances including proteins and polyamines, among them spermidine. Although spermidine is present in relatively low concentrations within semen, it plays a crucial role in sperm maturation and function.

 

Research indicates that spermidine influences sperm motility. Sperm lacking spermidine exhibit reduced motility, diminished vitality, and lower fertilization capacity. Consequently, spermidine is essential for normal sperm movement and fertilization capability.

 

 

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