What is 5-HTP?-Starting with an African seed
Griffonia Seed Extract 5-HTP is a key raw material for the human body to synthesize serotonin, which is known as the "happiness hormone" and regulates mood, sleep, and appetite,It occurs naturally in the seeds of a West African plant called Griffonia simplicifolia, which is traditionally used by locals to relieve anxiety. It can be called nature's "mood regulator."It is a natural source of the amino acid 5-HTP. This simplicifolia extract, obtained from the simplicifolia seed native to West Africa, has gained attention as a dietary supplement.Research suggests that it may be beneficial for overweight women.Can be made into different forms such as oral spray.

What Is 5-HTP Good For?
- The dual effect of day and night
| Daytime | Nighttime |
| →Converted into serotonin⬆️ | → Converted into melatonin⬆️ |
| Relieves anxiety and suppresses binge eating impulses | Shortens sleep onset time and improves deep sleep |


5-HTP In Food
1. Tryptophan Champion Group (→converted into 5-HTP in the body)
Turkey meat (150mg per 100g)
Pumpkin seeds (100mg per 30g) + bananas (rich in vitamin B6)
Classic sleep-promoting formula: warm milk + oats + almonds (synergistic effect of tryptophan + calcium + magnesium)
2. Direct Melatonin Foods
Sour cherry juice (100ml before bed), porcini mushrooms (add to stir-fries)
4 Sleep-promoting Ingredients
A sleep hormone secreted by the pineal gland in the human body, with secretion levels increasing at night and decreasing with age. Supplementing with melatonin can shorten the time it takes to fall asleep, with particularly noticeable effects in middle-aged and elderly people, earning it the reputation as the "golden sleep hormone."
- Griffonia Seed Extract 5-HTP
5-Hydroxytryptophan is an essential precursor for serotonin synthesis, helping to increase serotonin levels in the body. Serotonin aids in stabilizing mood, alleviating anxiety and stress, and promoting relaxation for easier sleep.
- Glycine
An endogenous amino acid in the human body with sedative properties. Studies show that taking glycine before bed can help you enter deep sleep faster, improve sleep quality, relax nerves, lower body temperature, and further enhance the sleep experience.
- L-Theanine
A natural amino acid derived from green tea, often referred to as the "natural sedative." L-theanine increases alpha wave activity in the brain, alleviates tension and anxiety, helps calm the mind and body, and makes it easier to fall asleep.

The synergistic effects of these multiple ingredients help improve sleep in various ways: melatonin resets the biological clock and induces sleepiness; 5-HTP increases serotonin levels and stabilizes mood, creating an environment conducive to sleep; glycine relaxes the nerves and deepens slow-wave sleep; and L-theanine relieves stress and promotes calmness. The complementary combination of these ingredients creates a more complete "deep sleep formula" that is more effective than a single ingredient.
5-HTP VS 5-HTP hydrate
Main difference: The main difference between the two is whether they contain crystalline water. CAS 4350-09-8 is the anhydrous form, while CAS 314062-44-7 is the hydrate form.
| Property | CAS 4350-09-8 | CAS 314062-44-7 |
|---|---|---|
| Chemical Name | 5-Hydroxy-L-tryptophan (5-HTP) | 5-Hydroxy-L-tryptophan hydrate (5-HTP hydrate) |
| Molecular Formula | C₁₁H₁₂N₂O₃ | C₁₁H₁₂N₂O₃·xH₂O |
| Molecular Weight | 220.22 | 220.22 + weight of water molecules |
| Appearance | White to off-white solid | White to off-white solid |
| Melting Point | 270–273 °C (decomposes) | Approx. 270 °C (decomposes) |
| Solubility | Soluble in water (approx. 10 mg/mL) | Soluble in water |
| Storage Conditions | 2–8 °C, protect from light | 2–8 °C, protect from light |
| Application Areas | Used as a dietary supplement; mood, sleep, appetite regulation | Same as left |
| Source | Chemically synthesized or extracted from Griffonia simplicifolia | Same as left |
| Special Notes | Anhydrous form | Contains crystal water; may affect purity and weight calculations |
Griffonia Seed Extract 5-HTP Powder Factory
Griffonia Seed Extract 5-HTP is directly exported to Europe and the United States in large quantities, If you want to order online, please contact us to get the price.





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