Organic Berberine Powder

Organic berberine powder is a traditional Chinese medicine ingredient extracted from plants such as Coptis chinensis and Phellodendron amurense. It is a natural isoquinoline alkaloid that is yellow in color and used for metabolic, anti-inflammatory, and antibacterial purposes.
Our factory supplies various berberine powders, including hydrochloride berberine, dihydroberberine, and tetrahydroberberine, which comply with international standards such as the United States Pharmacopeia (USP) and the European Pharmacopoeia (EP).
Since it is commonly used in the supplement industry, Sinov can customize raw material powders, capsules, or other forms of berberine powder, with a purity typically of 99%.We offer a range of OEM and ODM customization services, from raw materials to product design and logo design.



Metabolic Pathways Of Berberine
The primary metabolic pathways of berberine include demethylation, demethyleneation, reduction, hydroxylation, and subsequent conjugation reactions in the body. Active metabolites such as columbamine, berberine, and demethylberberine exhibit similar pharmacological effects to berberine, including antioxidant, anti-inflammatory, antitumor, antibacterial, hepatoprotective, neuroprotective, lipid-lowering, and hypoglycemic activities.
References:
Wang, K., Feng, X., Chai, L., Cao, S., & Qiu, F. (2017). The metabolism of berberine and its contribution to the pharmacological effects. Drug Metabolism Reviews, 49(2), 139–157.
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COA
Item | Specification / Requirement | Result |
---|---|---|
Product Name | Berberine Hydrochloride | |
CAS No. | 633-65-8 | |
Manufacturing Date | 2025-05-18 | |
Expiry Date | 2027-05-17 | |
Analysis Date | 2025-05-19 | |
Report Date | 2025-05-21 | |
Country of Origin | CHINA | |
Appearance | Yellow to brown powder | Complies |
Identification | Peak matches reference | Complies |
Assay | ≥ 98.0% | 99% |
Loss on Drying | ≤ 5.0% | 0.5% |
Residue on Ignition | ≤ 0.1% | 0.05% |
Chloride Content | 8.5% - 10.5% | 10% |
Related Substances | ||
- Berberine impurity A | ≤ 0.5% | 0.25% |
- Total impurity | ≤ 2.0% | 0.35% |
Microbial Limits | ||
- Total Plate Count | < 1000 cfu/g | < 100 cfu/g |
- Yeast & Moulds | < 100 cfu/g | < 10 cfu/g |
- E. Coli | Negative | Negative |
- Salmonella | Negative | Negative |
Conclusion | Conform with enterprise specification (Based on USP, EP, ChP) |
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1.Send the purchasing products, specifications, quantity, address and other information to us by e-mail.
2.The product manager will contact you at the first time.
3.PI will send to you.We can accept payment by Bank T/T,Western Union and Credited Card as well.
(The correct process information is that you confirm how much quantity you need → we will calculate the total amount for you including the freight → confirm that there is no problem to draft the order or PI → you arrange the payment → we will arrange the shipment to you → complete)
Disclaimer:
All information provided on this website is for reference and study only, no medical advice, not for diagnosis, treatment of disease.Sinov's bulk Berberine powder is not recommended for personal use.
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