Methylene Blue Trihydrate Vs Methylene Blue

Nov 12, 2025

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Methylene Blue Trihydrate Vs Methylene Blue

 

Name Methylene Blue Trihydrate Methylene Blue
CAS NO. 7220-79-3 61-73-4
Purity Purity 99% Purity 99%
Structural formula Methylene Blue Trihydrate Methylene Blue
Solubility Soluble in water, chloroform; sparingly soluble in ethanol Soluble in water, ethanol, ethylene glycol, methyl cellosolve

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Methylene Blue Trihydrate and Methylene Blue are two similar substances, but they are not the same. We will analyze the similarities and differences between them from several aspects such as appearance, purity, and application.

 

From the perspective of chemical structure:
Methylene Blue is a common substance, while Methylene Blue Trihydrate is the trihydrate form of the former, and the active ingredients are the same.


From the aspect of appearance:
Both are usually in powder form, in a crystalline powder state. Methylene Blue is a dark green crystalline powder, while Methylene Blue Trihydrate is a dark blue-green crystalline powder.

 

Methylene Blue Trihydrate


In terms of the content of the powder:

Methylene Blue does not contain crystalline water. Under the same weight condition, the proportion of the effective substances may be higher. However, both can be produced into 99% pure high-purity powder during the production process.

 


In terms of stability:
The properties of Methylene Blue Trihydrate are more stable and are mostly used in industrial fields and experiments.

 

 

Methylene Blue trihydrate Chemical Properties
Melting point 190 °C (dec.)(lit.)
bulk density 400-600kg/m3
density 0.98 g/mL at 25 °C
Fp 14 °C
storage temp. no restrictions.
solubility Soluble in water, chloroform; sparingly soluble in ethanol
Colour Index 52015
form Solid
pka 2.6, 11.2(at 25℃)
color Green
PH 3 (20°C, 10g/L in H2O)
Water Solubility 4 g/100 mL

 

Methylene Blue Chemical Properties
Melting point 190 °C (dec.)(lit.)
density 1.0 g/mL at 20 °C
refractive index n20/D1.347
Fp 45 °C
storage temp. room temp
solubility Soluble in water, ethanol, ethylene glycol, methyl cellosolve
form Liquid
Colour Index 52015
pka 2.6, 11.2(at 25℃)
color Green
Specific Gravity 0.98
Odor Odorless
Water Solubility 40 g/L (20 ºC)

 

 

What Are The Similarities Between Methylene Blue Trihydrate And Methylene Blue?

 

Methylene blue trihydrate and methylene blue share similar spectral characteristics. In terms of application fields, they are used in cases of methemoglobinemia and various dyes, etc.

high quality Methylene Blue Trihydrate  7220-79-3 powder

High-purity methylene blue trihydrate and methylene blue powder supplier, meeting pharmaceutical grade, industrial grade and other standards.Bulk Pricing Available.Ready to Ship.

 COA

Product name Methylene Blue Trihydrate Manufacture date Jun.13.2025
Batch number SN250613 Analysis date Jun.14.2025
Batch quantity 500kg Expiry date Jun.13.2027

Items

Standard

Results

Characters

Dark green to dark brown powder

Qualified

Identification

Meets the requirements

Qualified

Appearance of solution

Meets the requirements

Qualified

Organic volatile impurities

Meets the requirements

Qualified

Heavy metals

≤0.002%

Qualified

Loss on drying

≤18.0%

14.3%

Residue on ignition

≤0.1%

0.03%

Assay

99.0%

99.3%

CONCLUSION:

Complies to the standards

 

Packing description: Sealed export grade drum & double of sealed plastic bag
Storage: Store in cool & dry place not freeze., keep away from strong light and heat
Shelf life: 2 years when properly stored

 

If you have any needs in this regard, please contact us to obtain samples and the lowest price. sinov@pharmachemm.com

 

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