What is 1,7-Dimethylxanthine?
1,7-Dimethylxanthine(CAS 611-59-6), more commonly known as paraxanthine, is a naturally occurring metabolite of caffeine. After ingestion, caffeine is primarily metabolized in the liver by cytochrome P450 enzymes (mainly CYP1A2), producing paraxanthine as the dominant metabolite.Parparaxanthine is a functional raw material powder.
Chemically, it belongs to the xanthine class of alkaloids, which also includes caffeine, theobromine, and theophylline. Compared to caffeine, 1,7-Dimethylxanthine has a similar core structure but exhibits distinct pharmacokinetic and physiological properties.
How Does 1,7-Dimethylxanthine Work in the Body?
Adenosine Receptor Antagonism
Like caffeine, paraxanthine acts as a competitive antagonist of adenosine receptors (primarily A1 and A2A). By blocking adenosine signaling, it reduces feelings of fatigue and promotes alertness.
Modulation of Lipolysis
Paraxanthine has been shown to enhance lipolysis (the breakdown of fats into free fatty acids). This occurs partly through increased intracellular cyclic AMP (cAMP) levels, which activate hormone-sensitive lipase.
Central Nervous System Stimulation
It contributes to increased neuronal activity and neurotransmitter release, supporting cognitive performance and mental clarity, although its stimulant profile may differ slightly from caffeine.
Improved Muscle Function
Some studies suggest paraxanthine may enhance skeletal muscle contractility and physical performance, potentially via calcium ion mobilization within muscle cells.
Applications of 1,7-Dimethylxanthine
Based on current scientific understanding and emerging research, 1,7-dimethylxanthine has several potential applications:
1.Dietary Supplements
Used in formulations targeting energy, focus, and metabolic support, particularly as an alternative or complement to caffeine.
2.Sports Nutrition
As a Sport Nutrition ingredient, Incorporated into pre-workout and performance-enhancing products, where its effects on fat metabolism and muscle function are of interest.
3.Cognitive Health Products
Explored in nootropic formulations aimed at improving alertness, attention, and mental performance.
Procurement Considerations
For procurement, it is important to ensure high purity, reliable sourcing, and compliance with regulatory standards, as research on its direct use as an ingredient is still evolving. Selecting qualified suppliers with transparent quality documentation is essential for product development and commercialization.
Product-related parameters
| CAS: | 611-59-6 |
| MF: | C7H8N4O2 |
| MW: | 180.16 |
| Appearance: | White Powder |
|
Purity: |
99% |
| Shelf life: | 2 years |
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Disclaimer:
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