What Is Magnolol?
Magnolol is a bioactive compound isolated from the bark of Magnolia officinalis or Magnolia grandiflora, belonging to the lignan family of organic compounds. It has been used in traditional Asian medicine to treat anxiety, sleep disorders, and allergic diseases. It also exhibits antifungal activity, anti-periodontal disease activity, and various osteoblast-stimulating and osteoclast-inhibiting activities.
| Product Name: | Magnolol |
| Synonyms: | 5,5'-DIALLYL-BIPHENYL-2,2'-DIOL;5,5'-DIALLYL-2,2'-BIPHENYLDIOL;5,5'-DIALLYL-2,2'-DIHYDROXYBIPHENYL;HONOKIOL(P);MAGNOLOL(SH);5',5-di-2-propenyl-(1,1'-Biphenyl)-2,2'-diol;MAGNOLOL;Magnolia officinalis Rehd.et Wils |
| CAS: | 528-43-8 |
| MF: | C18H18O2 |
| MW: | 266.33 |
| EINECS: | 610-903-7 |
| Mol File: | 528-43-8.mol |
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Magnolol In Skin Care

Research indicates that changes in facial morphology with age are primarily associated with three factors: reduced subcutaneous fat, skeletal atrophy, and skin tissue displacement. Beneath the skin lies an important layer of fat tissue (sWAT), which not only stores energy but also secretes various substances that maintain skin health. However, as we age, the body's ability to produce new fat cells diminishes, and the regenerative and transformative functions of preadipocytes (fat stem cells) also weaken.
Additionally, there is a special layer of fat (dWAT) in the deeper layers of the skin, primarily distributed around the roots of hair follicles. This fat undergoes significant changes when exposed to excessive sunlight, not only shrinking in volume but also being replaced by fibrous tissue, leading to scar-like alterations. Therefore, scientists believe that protecting dWAT may represent a new direction in combating skin aging.
Magnolol is a natural polyphenol component extracted from magnolia bark. Experimental results show that it can induce preadipocytes in mice to differentiate into fat cells, thereby exerting a skin-plumping effect.

Magnolia officinalis has remarkable anti-aging properties in cosmetics, particularly for skin aging caused by chronic inflammation. It contains abundant magnolol (magnolol) and magnolol, which can achieve anti-inflammatory effects by inhibiting the activation of IKK enzymes caused by free radicals, thereby preventing the activation of NF-κB inflammatory factors.
Technical Specification
| ANALYSIS | SPECIFICATION | RESULTS | Remark |
| Appearance | White fine powder | Complies | Visual |
| Odor | Characteristic | Complies | Organoleptic |
| Tasted | Characteristic | Complies | Organoleptic |
| Assay(Honokiol) | 5% Min | 5.27% | HPLC |
| Sieve Analysis | 100% pass 80 mesh | Complies | |
| Loss on Drying | 2% Max. | 2.76% | |
| Sulphated Ash | 5% Max. | 3.18% | |
| Extract Solvent | Alcohol & Water | Complies | |
| Heavy Metal | 5ppm Max | Complies | AAS |
| As | 2ppm Max | Complies | AAS |
| Residual Solvents | 0.05% Max. | Negative | GC |
| Microbiology | |||
| Total Plate Count | 10000/g Max | Complies | |
| Yeast & Mold | 100/g Max | Complies | |
| E.Coli | Negative | Complies | |
| Salmonella | Negative | Complies |
Note:The above COA is for reference only. Please contact us for specific COA values.
Packing And Shipping
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Packing |
1kg/bag ,25kg/bag;25kg/drum; according to your requirements |
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Transit |
Fedex, TNT,DHL,EMS,and so on. |
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Port |
Shanghai/Tianjin/Dalian/Beijing/Xi'an |
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Lead Time |
3-5 working days upon received the payment |
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For mass orders, it will be delivered by air or sea. |
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How to contact us
1.Send the purchasing products, specifications, quantity, address and other information to us by e-mail.
2.The product manager will contact you at the first time.
3.After all negotiations, sign the purchase contract.
4.Delivery after payment for stock, and start production after payment for large special products.
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