Andrographolide Powder

Andrographolide Powder
Details:
Latin Name: Andrographis paniculata
CAS No.:5508-58-7
Molecular Formula:C20H30O5
Molecular Weight:350.45
Botanical Source: Andrographis paniculate
Other names:Kariyt Extract
Brand:Sinov
Shelf life:2 Years
Sample is Available
Similar Product:NMN,NRCL,NADH,NADP
COA, HPLC, MSDS available
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Description
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Natural Andrographolide Powder Wholesale Supplier 

Products Description

 

 

Andrographis paniculata is a health food widely used in India, China, and Southeast Asia. It contains the pharmacologically active compound andrographolide, the primary active ingredient in the natural plant Andrographis paniculata, which has liver-protecting properties. Extracted andrographolide typically exists as white powder.Andrographolide Powder can be used as a raw material additive for health supplement.

 

Andrographolide Powder Wholesale

 

 

Active Ingredients

 

 

Andrographolide 5%-98% Min (HPLC)
Dehydroandrographolide 5-95% Min (HPLC)
Deoxyandrographolide 98% Min (HPLC)
Neoandrographolide 98% Min (HPLC)

 

Andrographolide 98%

 

 


Andrographolide exhibits anti-hepatotoxic activity, but its bioavailability is limited by rapid clearance and high plasma protein binding. Studies have shown that andrographolide herb encapsulation at 25 and 50 mg kg(-1) of andrographolide protects the liver in rats, potentially improving bioavailability and enhancing hepatoprotective activity.

 

Andrographolide can delay the progression of nephrotic syndrome (DN) and high glucose (HG)-induced mesangial cell dysfunction. An in vitro study demonstrated that 5 and 10 μM andrographolide effectively inhibited HG-induced apoptosis, epithelial-mesenchymal transition (EMT), and collagen deposition in HK-2 cells. Andrographolide exhibits significant protective effects against HG-induced renal tubular injury and fibrosis, and its mechanism involves the maintenance of mitochondrial function and inhibition of the NLRP3 inflammasome.

 

 

 

1. Andrographolide protects the skin from acne.

2. Andrographolide is used to lower blood sugar and has antiviral properties that appear to inhibit the glycoprotein in viruses. This hinders the ability of viruses to invade cells in the body and replicate.

3. Andrographolide has antibacterial properties

4. Andrographolide kills intestinal worms and protects the intestinal tract.

5. Andrographolide can reduce swelling and decrease capillary leakage.

6. Andrographolide can also reduce symptoms caused by diarrhea and bacterial infections.

7. Andrographolide has the function of promoting the discharge of mucus from the respiratory system.

8. Andrographolide helps to reduce the symptoms of people suffering from the common cold. Andrographolide is also said to reduce fertility.

Andrographis 3%

Andrographide 3%

Andrographis 98%

Andrographide 98%

AndrographiS OEM

Andrographide OEM ODM

 

 

Certificate of Analysis

 

 

Item Specification Result
Andrographolide 98% 98.20%
Organoleptic Tests
Appearance White powder Conform
Physical Characteristics
Odor Characteristic Conform
Taste Characteristic Conform
Loss on Drying 1.0% Max. 0.65%
Sieve 98% pass 80 mesh Conform
Heavy Metals
Total Heavy Metals 10ppm Max. Conform
Lead (Pb) 2ppm Max. Conform
Arsenic (As) 1ppm Max. Conform
Mercury (Hg) 1ppm Max. Conform
Microbe Tests
Total Plate Count NMT 1000cfu/g Conform
Total Yeast & Mold NMT 1000cfu/g Conform
E. Coli Negative Negative
Salmonella Negative Negative

 

 

 

Application

 

 

1.The compound called Andrographolide is formulated into a powder form and is used to treat acute bacterial dysentery, gastroenteritis and pneumonia in poultry and livestock.

2.Andrographolide is usually formulated into tablets and soft capsules in the fields of health supplements and other products.

Andrographolide capsule  Andrographolide capsule

 

 

 

Andrographolide The Same As Andrographis?

 

 

Andrographis paniculata is used in traditional medicine for its immune-boosting, anti-inflammatory and antiviral properties, and the whole plant or its extracts contain a wide range of biologically active compounds, including flavonoids and diterpenes.

 

Andrographolide is a specific bioactive diterpene compound isolated from Andrographis paniculata and is one of the main compounds of the plant with medicinal properties, and studies have shown it to have anti-inflammatory, antioxidant and potentially anti-cancer properties.

Key Differences:


-Andrographis paniculata is a plant, while andrographolide is a chemical constituent of the plant.

 

 

Natural Andrographide Powder Factory
 

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For cosmetic ingredients, plant extracts, and supplement ingredients, the company has extensive OEM ODM experience and can customize labels, packaging, and other content.

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1.Send the purchasing products, specifications, quantity, address and other information to us by e-mail.

2.The product manager will contact you at the first time.

3.After all negotiations, sign the purchase contract.

4.Delivery after payment for stock, and start production after payment for large special products.

Disclaimer:

All information provided on this website is for reference and study only, no medical advice, not for diagnosis, treatment of disease.

Reference:

Maiti, Kuntal, et al. "Enhancing Bioavailability and Hepatoprotective Activity of Andrographolide from Andrographis paniculata through Its Herbosome." Journal of the Science of Food and Agriculture, vol. 90, no. 1, 2010, pp. 43–51. DOI:10.1002/jsfa.3777

Zhou P, et al. Andrographolide protects against diabetic tubular injury and fibrosis by suppressing mitochondrial dysfunction and NLRP3 inflammasome activation. Phytomedicine. 2021;79:153277. 

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