Natural Andrographolide Powder Wholesale Supplier
Products Description
Andrographis paniculata is a health food widely used in India, China, and Southeast Asia. It contains the pharmacologically active compound andrographolide, the primary active ingredient in the natural plant Andrographis paniculata, which has liver-protecting properties. Extracted andrographolide typically exists as white powder.Andrographolide Powder can be used as a raw material additive for health supplement.

Active Ingredients
Andrographolide 5%-98% Min (HPLC)
Dehydroandrographolide 5-95% Min (HPLC)
Deoxyandrographolide 98% Min (HPLC)
Neoandrographolide 98% Min (HPLC)

Andrographolide exhibits anti-hepatotoxic activity, but its bioavailability is limited by rapid clearance and high plasma protein binding. Studies have shown that andrographolide herb encapsulation at 25 and 50 mg kg(-1) of andrographolide protects the liver in rats, potentially improving bioavailability and enhancing hepatoprotective activity.
Andrographolide can delay the progression of nephrotic syndrome (DN) and high glucose (HG)-induced mesangial cell dysfunction. An in vitro study demonstrated that 5 and 10 μM andrographolide effectively inhibited HG-induced apoptosis, epithelial-mesenchymal transition (EMT), and collagen deposition in HK-2 cells. Andrographolide exhibits significant protective effects against HG-induced renal tubular injury and fibrosis, and its mechanism involves the maintenance of mitochondrial function and inhibition of the NLRP3 inflammasome.
1. Andrographolide protects the skin from acne.
2. Andrographolide is used to lower blood sugar and has antiviral properties that appear to inhibit the glycoprotein in viruses. This hinders the ability of viruses to invade cells in the body and replicate.
3. Andrographolide has antibacterial properties
4. Andrographolide kills intestinal worms and protects the intestinal tract.
5. Andrographolide can reduce swelling and decrease capillary leakage.
6. Andrographolide can also reduce symptoms caused by diarrhea and bacterial infections.
7. Andrographolide has the function of promoting the discharge of mucus from the respiratory system.
8. Andrographolide helps to reduce the symptoms of people suffering from the common cold. Andrographolide is also said to reduce fertility.

Andrographide 3%

Andrographide 98%

Andrographide OEM ODM
Certificate of Analysis
| Item | Specification | Result |
|---|---|---|
| Andrographolide | 98% | 98.20% |
| Organoleptic Tests | ||
| Appearance | White powder | Conform |
| Physical Characteristics | ||
| Odor | Characteristic | Conform |
| Taste | Characteristic | Conform |
| Loss on Drying | 1.0% Max. | 0.65% |
| Sieve | 98% pass 80 mesh | Conform |
| Heavy Metals | ||
| Total Heavy Metals | 10ppm Max. | Conform |
| Lead (Pb) | 2ppm Max. | Conform |
| Arsenic (As) | 1ppm Max. | Conform |
| Mercury (Hg) | 1ppm Max. | Conform |
| Microbe Tests | ||
| Total Plate Count | NMT 1000cfu/g | Conform |
| Total Yeast & Mold | NMT 1000cfu/g | Conform |
| E. Coli | Negative | Negative |
| Salmonella | Negative | Negative |
1.The compound called Andrographolide is formulated into a powder form and is used to treat acute bacterial dysentery, gastroenteritis and pneumonia in poultry and livestock.
2.Andrographolide is usually formulated into tablets and soft capsules in the fields of health supplements and other products.

Andrographolide The Same As Andrographis?
Andrographis paniculata is used in traditional medicine for its immune-boosting, anti-inflammatory and antiviral properties, and the whole plant or its extracts contain a wide range of biologically active compounds, including flavonoids and diterpenes.
Andrographolide is a specific bioactive diterpene compound isolated from Andrographis paniculata and is one of the main compounds of the plant with medicinal properties, and studies have shown it to have anti-inflammatory, antioxidant and potentially anti-cancer properties.
Key Differences:
-Andrographis paniculata is a plant, while andrographolide is a chemical constituent of the plant.
Natural Andrographide Powder Factory
If you want to order online, please contact us to get the price

OEM ODM Service
For cosmetic ingredients, plant extracts, and supplement ingredients, the company has extensive OEM ODM experience and can customize labels, packaging, and other content.


How to contact us
1.Send the purchasing products, specifications, quantity, address and other information to us by e-mail.
2.The product manager will contact you at the first time.
3.After all negotiations, sign the purchase contract.
4.Delivery after payment for stock, and start production after payment for large special products.
Disclaimer:
All information provided on this website is for reference and study only, no medical advice, not for diagnosis, treatment of disease.
Reference:
Maiti, Kuntal, et al. "Enhancing Bioavailability and Hepatoprotective Activity of Andrographolide from Andrographis paniculata through Its Herbosome." Journal of the Science of Food and Agriculture, vol. 90, no. 1, 2010, pp. 43–51. DOI:10.1002/jsfa.3777
Zhou P, et al. Andrographolide protects against diabetic tubular injury and fibrosis by suppressing mitochondrial dysfunction and NLRP3 inflammasome activation. Phytomedicine. 2021;79:153277.

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