What Is Polydeoxyribonucleotide?
Olydeoxyribonucleotide, also known as DNA Sodium Salt-commonly referred to as PDRN-is a DNA substance extracted from the testes of purebred salmon. It is utilized in biological reagents and medical aesthetic products.
PDRN first appeared in medical aesthetic procedures. Its full name is Polydeoxyribonucleotide, which simply refers to a combination of DNA fragments. Additionally, there is a similar substance called PN; the two have no fundamental differences, and people typically distinguish them based on molecular weight.
Jinan Sinov Biotechnology PDRN Quality Standards
| Test Item | Test Standard |
|---|---|
| Appearance | White or off-white solid, free of visible impurities and discoloration |
| Odor | Odorless |
| Loss on Drying | ≤15% (w/w) |
| pH | 6.0–8.0 |
| Residue on Ignition | ≤30% (w/w) |
| Heavy Metals (as Pb) | ≤10 μg/g |
| Protein Content | ≤1% (w/w) |
| Identification | The absorbance ratio at 260 nm/280 nm should be 1.8–2.0 |
| Content (on dry basis) | ≥99% (w/w) |
| Average Molecular Weight | ≥1000 kDa |
| Molecular Weight Distribution | ≤2.0 |
| Transmittance | ≥99% |
Jinan Sinov Biotechnology PN Quality Standards
| Test Item | Test Standard |
|---|---|
| Appearance | White or off-white solid, free of visible impurities and discoloration |
| Odor | Odorless |
| Loss on Drying | ≤15% (w/w) |
| pH | 6.0–8.0 |
| Residue on Ignition | ≤30% (w/w) |
| Heavy Metals (as Pb) | ≤10 μg/g |
| Protein Content | ≤1% (w/w) |
| Identification | The absorbance ratio at 260 nm/280 nm should be 1.8–2.0 |
| Content (on dry basis) | ≥99% (w/w) |
| Average Molecular Weight | ≥2000 kDa |
| Molecular Weight Distribution | ≤2.0 |
| Transmittance | ≥99% |
| Color Enhancement Effect | ≥30% |
| Molar Extinction Coefficient | 13000–15000 |
Why extract salmon DNA for facial injections? It's said that salmon DNA shares remarkable similarity with human DNA, with over 98% sequence identity. Once introduced into our skin, this DNA binds to adenosine receptors within the skin cells, thereby regulating downstream signaling pathways. This process delivers notable benefits in skin repair and anti-aging, particularly demonstrating exceptional efficacy in wound healing. Consequently, it has been adopted as a material in medical aesthetics.
Salmon DNA-derived PDR and PhytoPDRN are two of the latest trending products in the medical aesthetics industry. The emergence of PDRN and PN raw materials may further accelerate the development of the medical skincare sector. If you are interested in either of these ingredients, please contact us for more information and pricing.
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Disclaimer:
All information provided on this website is for reference and study only, no medical advice, not for diagnosis, treatment of disease.
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