What is Spermidine?
Spermidine abbreviated as SPD, with the molecular formula H2N(CH2)3NH(CH2)4NH2, is a triamine polyamine substance. Spermidine is 1 kind of hydrocarbon with a "zigzag" long serpentine skeleton composed of 7 carbon atoms and with amino groups at both ends and in the middle.
Anti-aging mechanism of spermidine
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The father of the microscope, Levenhuk, was looking at his own semen through a homemade microscope more than three years ago when he accidentally discovered a variety of polyamines, including what is now known as spermidine.
As the body ages, the concentration of intracellular spermidine generally declines, but the exception is the ultra-elderly, where studies have found that centenarians still have very high levels of spermidine in their blood. Its role is to reduce inflammation and activate the "self-cleaning mode" of human cells (i.e. autophagy).
As cells age, mitochondria can no longer provide energy to the cell and therefore begin to self-destruct, and Spermidine triggers autophagy within the mitochondria to induce internal remodeling of the mitochondria.
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